Whey Protein Isolate (90%) (Instantized) – 27,250 mg
Whey protein isolate is one of the highest-quality protein sources available, providing rapidly absorbed essential amino acids (EAAs) that support skeletal muscle repair, adaptation, and recovery after training. Because of its exceptionally high leucine content and complete amino acid profile, whey protein is widely considered the gold standard for stimulating muscle protein synthesis (MPS).
- Delivers all nine essential amino acids required for muscle repair and remodeling.
- Rapid digestion produces a sharp rise in circulating amino acids, maximizing the post-exercise anabolic response.
- Rich in naturally occurring leucine, the primary amino acid responsible for activating mTORC1, the central regulator of muscle protein synthesis.
- Consistently outperforms slower proteins for stimulating acute MPS following resistance exercise.
- Extremely low lactose; often tolerable for lactose intolerant individuals.
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Supports strength gains, lean mass development, and improved recovery when consumed consistently alongside resistance training.
Synergy: Whey protein provides the complete amino acid substrate required for muscle repair, while PepForm® Leucine Peptides rapidly increase leucine delivery to maximize anabolic signaling. Together they help reach and exceed the leucine threshold while supplying sufficient EAAs to sustain protein synthesis.
- Tang JE et al. J Appl Physiol. 2009.
- Moore DR et al. Am J Clin Nutr. 2009.
- Phillips SM. Nutr Metab. 2014.
- Morton RW et al. Br J Sports Med. 2018.
PepForm® Leucine Peptides – 1,150 mg
PepForm® is a patented leucine peptide ingredient that delivers leucine bound to peptides rather than as free-form amino acid. This peptide-bound delivery system has been shown to improve amino acid transport and rapidly elevate circulating leucine, enhancing the anabolic response following exercise.
Leucine is the primary nutritional trigger for muscle protein synthesis through activation of the mTOR signaling pathway. Research suggests that maximizing post-exercise MPS requires approximately 2.5–3.0 grams of leucine per serving. PROTEGEN provides over 3.1 grams of leucine, exceeding this threshold.
- Helps exceed the leucine threshold associated with maximal stimulation of muscle protein synthesis.
- Activates mTOR signaling, increasing muscle protein synthesis (MPS).
- May reduce muscle protein breakdown (MPB) indirectly by shifting net muscle protein balance toward anabolism when adequate EAAs are present.
- Supports greater recovery and adaptation following resistance training.
- Provides peptide-bound leucine designed for efficient intestinal uptake.
Synergy: Combined with the naturally high leucine content of whey isolate, PepForm® elevates total leucine approximately 21% above a typical whey isolate, helping maximize MPS while the complete EAA profile supports sustained muscle remodeling.
- Norton LE & Layman DK. J Nutr. 2006.
- Churchward-Venne TA et al. J Physiol. 2012.
- Atherton PJ et al. J Physiol. 2010.
- van Vliet S et al. J Nutr. 2015.
Tart Cherry (Prunus cerasus) extract (fruit) – 250 mg
Tart cherry is a naturally rich source of anthocyanins and polyphenols that help support recovery following strenuous exercise. Research suggests tart cherry supplementation may reduce exercise-induced muscle soreness while supporting recovery of strength and performance after intense training.
- Rich in anthocyanins with antioxidant activity.
- Helps reduce exercise-induced muscle soreness.
- Supports recovery of muscular strength following strenuous exercise.
- May reduce biomarkers of exercise-induced oxidative stress.
- Supports athletes performing repeated bouts of high-intensity training.
Synergy: While whey protein and leucine stimulate muscle rebuilding, tart cherry helps create a recovery environment by reducing exercise-induced muscle damage and soreness, allowing athletes to train at a higher frequency.
- Bell PG et al. Scand J Med Sci Sports. 2016.
- Connolly DAJ et al. Br J Sports Med. 2006.
- Howatson G et al. Scand J Med Sci Sports. 2010.
DigeSEB® Sport – 100 mg
DigeSEB® Sport combines digestive enzymes with probiotic strains specifically selected to improve protein digestion and gastrointestinal tolerance during periods of high protein intake. Efficient digestion allows more dietary protein to be broken down into absorbable amino acids that can be utilized for muscle recovery.
- Supports digestion of high-protein meals.
- Helps improve amino acid availability from dietary protein.
- Contains clinically studied digestive enzymes and probiotic strains.
- Supports gastrointestinal comfort.
- May reduce digestive discomfort associated with high-protein diets.
Synergy: Efficient protein digestion ensures the amino acids supplied by whey protein and PepForm® are fully available for muscle protein synthesis while supporting digestive comfort for athletes consuming large amounts of protein.
- Roxas M. Altern Med Rev. 2008.
- Williams J et al. Nutrients. 2021.
- Bacillus probiotic literature supporting digestive enzyme production and protein utilization.
AstraGin® – 50 mg
AstraGin® is a patented botanical ingredient derived from Panax notoginseng and Astragalus membranaceus that has been shown in preclinical and human research to support intestinal nutrient transport. It appears to enhance expression of amino acid and glucose transporters involved in nutrient absorption.
- Supports intestinal nutrient uptake.
- May increase amino acid transporter expression.
- Supports efficient utilization of dietary protein.
- Helps optimize recovery nutrition.
- Supports overall gastrointestinal function.
Synergy: AstraGin® complements DigeSEB® Sport by supporting both digestion and absorption—helping maximize the delivery of amino acids generated from whey protein and PepForm® to skeletal muscle.
- Luo X et al. J Agric Food Chem. 2018.
- NuLiv Science technical and published transporter research.
- Wang Y et al. Phytother Res. 2020.
Why PROTEGEN is Different
Compared to a typical whey protein isolate, PROTEGEN is formulated to optimize every stage of the recovery process, from anabolic signaling to nutrient delivery and muscle repair.
Compared to a typical whey protein isolate, each serving provides:
- 20.9% more leucine (3,105 mg vs. 2,568 mg)
- 17.6% more BCAAs (6,256 mg vs. 5,319 mg)
- 12.4% more EAAs (12,740 mg vs. 11,335 mg)
This combination helps:
- Reach and exceed the leucine threshold required for maximal MPS.
- Increase muscle protein synthesis (MPS).
- Reduce net muscle protein breakdown (MPB) through improved anabolic balance.
- Support faster recovery between training sessions.
- Enhance adaptation to resistance training while improving protein digestion and nutrient utilization.
Based on its enhanced amino acid profile and the complementary actions of PepForm®, AstraGin®, DigeSEB® Sport, and tart cherry extract, PROTEGEN is designed to provide:
- ~30–45% greater muscle protein synthesis (MPS) signaling efficiency through higher leucine delivery, exceeding the >3 g leucine threshold, stronger mTOR activation, and a more robust essential amino acid profile.
- ~15–25% greater support for reducing muscle protein breakdown (MPB) and exercise-induced muscle damage, promoting a more favorable net protein balance while tart cherry extract helps reduce post-exercise soreness.
- ~15–25% greater recovery potential by combining enhanced protein synthesis, improved nutrient utilization, and reduced muscle soreness to help athletes recover between training sessions.
- ~25–35% greater amino acid delivery and utilization potential through the combined effects of PepForm® leucine peptides, AstraGin®, DigeSEB® Sport, and an intrinsically higher leucine, BCAA, and EAA content.
Projected Effective Aminos Acid Delivery
Using a theoretical model that assumes approximately 12% greater effective amino acid delivery through enhanced nutrient absorption (for illustration only, not measured in the finished product), PROTEGEN could provide the equivalent of:
- +35.4% effective leucine delivery
- +31.7% effective BCAA delivery
- +25.9% effective EAA delivery
These projected advantages build upon PROTEGEN’s already superior amino acid profile, which provides 20.9% more leucine, 17.6% more BCAAs, and 12.4% more EAAs than a typical whey protein isolate.