Katuki (Picrorhiza kurroa) Extract (Rhizome) - 750mg

A traditional Ayurvedic herb used primarily for liver protection and detoxification.

• Supports liver enzyme balance and healthy bile secretion
• Promotes hepatocyte regeneration and detoxification pathways
• Provides antioxidant defense against free radical damage
• May support healthy inflammatory responses in liver tissues
• Contributes to metabolic waste elimination

Synergy: Combines effectively with Milk Thistle and TUDCA to protect and restore liver cells.

• Dwivedi Y. Indian J Pharmacol. 2007;39(3):125–131.
• Anand V et al. Indian J Biochem Biophys. 1994;31(4):252–255.
• Chander R et al. Phytother Res. 1993;7(4):275–279.

 

N-Acetyl L-Cysteine (NAC) - 600mg

A cysteine derivative that replenishes intracellular glutathione and supports detoxification.

• Acts as a precursor for glutathione synthesis, the body’s master antioxidant
• Supports phase II liver detoxification pathways
• Helps protect against oxidative damage to liver and kidney cells
• May aid in reducing toxin load and heavy metal burden
• Supports respiratory health and mucolytic activity

Synergy: Works synergistically with Setria® Glutathione and Milk Thistle to enhance glutathione status and detoxification.

• Rushworth GF et al. Clin Pharmacol. 2014;6:117–125.
• Samuni Y et al. Biochim Biophys Acta. 2013;1830(5):4117–4129.
• Kelly GS. Altern Med Rev. 1998;3(2):114–127.

 

Clove (Syzygium aromaticum) Extract (Flower) - 250mg

A botanical extract rich in eugenol, known for antioxidant and antimicrobial effects.

• Provides potent antioxidant capacity to neutralize free radicals
• Supports healthy inflammatory balance
• Contributes to microbial balance in the gut and oral cavity
• May protect liver tissues from oxidative stress
• Supports metabolic and immune function

Synergy: Complements Katuki and NAC by providing broad-spectrum antioxidant defense.

• Chaieb K et al. Phytother Res. 2007;21(6):501–506.
• Gülçin I et al. J Agric Food Chem. 2004;52(21):5039–5045.
• Prashar A et al. Food Chem. 2006;99(4):984–989.

 

Milk Thistle (Silybum marianum) Extract (Seed) (std. min. 80% Silymarin) - 250mg

A standardized extract supporting liver cell protection and regeneration.

• Stabilizes hepatocyte membranes against toxin damage
• Enhances glutathione content in liver cells
• Supports bile production and digestive detoxification
• Provides anti-inflammatory and antifibrotic activity
• May help regenerate damaged liver tissue

Synergy: Pairs with Katuki and TUDCA for a comprehensive liver-protective matrix.

• Pradhan SC et al. Indian J Med Res. 2006;124(5):491–504.
• Saller R et al. Phytomedicine. 2008;15(5):396–405.
• Polyak SJ et al. Hepatology. 2010;51(6):1919–1926.

 

Setria® (L-Glutathione Reduced) - 250mg

A branded form of bioavailable, reduced glutathione supporting cellular antioxidant defense.

• Replenishes intracellular glutathione stores
• Supports detoxification of heavy metals, xenobiotics, and reactive intermediates
• Protects mitochondrial and DNA integrity
• Contributes to immune resilience and balanced inflammatory responses
• May support skin health and overall oxidative defense

Synergy: Works with NAC and Milk Thistle to maximize glutathione replenishment and detoxification capacity.

• Richie JP et al. Eur J Nutr. 2015;54(2):251–263.
• Allen J et al. Nutrients. 2011;3(4):343–369.
• Witschi A et al. Eur J Clin Pharmacol. 1992;43(6):667–669.

 

Tauroursodeoxycholic Acid (TUDCA) - 250mg

A bile acid derivative supporting liver cell protection, bile flow, and metabolic health.

• Reduces endoplasmic reticulum stress in hepatocytes
• Promotes bile secretion and reduces cholestasis
• Protects mitochondrial function in liver cells
• May help stabilize cell membranes against toxins
• Supports healthy liver enzyme levels

Synergy: Complements Katuki, Milk Thistle, and NAC for complete liver detoxification and restoration.

• Beuers U et al. Hepatology. 1992;15(3):404–410.
• Amaral JD et al. J Hepatol. 2009;50(4):720–733.
• Rodrigues CM et al. Gastroenterology. 1998;115(3):765–777.

 

Synergy Overview

Liver Protection & Regeneration: Katuki, Milk Thistle, and TUDCA synergistically protect hepatocytes, enhance bile flow, and restore liver enzyme balance.

Glutathione & Antioxidant Defense: NAC, Setria® Glutathione, and Clove provide multi-layered antioxidant support to neutralize free radicals and oxidative stress.

Detoxification & Metabolic Support: NAC and Glutathione promote phase II detoxification, while Milk Thistle and Katuki support metabolic waste elimination.

Mitochondrial & Cellular Stability: TUDCA and Glutathione help preserve mitochondrial integrity and endoplasmic reticulum function under stress.

 

FAQ

Q: What is this formula designed to do?

A: This product is engineered for advanced liver detoxification, cellular antioxidant protection, and bile flow optimization. It blends clinically studied compounds for comprehensive hepatoprotection and phase I/II detox support.

Q: What are the key ingredients and what do they do?

A:

·       Katuki (750mg): A bitter Ayurvedic herb that supports bile secretion, liver enzyme balance, and hepatocyte protection

·       N-Acetyl L-Cysteine (NAC) (600mg): Boosts glutathione production and supports liver detox pathways

·       Clove Extract (250mg): Potent antioxidant and antimicrobial with benefits for gut-liver axis and inflammation

·       Milk Thistle (250mg, 80% Silymarin): Classic liver protectant that helps stabilize hepatocyte membranes

·       Setria® Reduced Glutathione (250mg): Patented, bioavailable form of glutathione to combat oxidative stress and toxins

·       TUDCA (250mg): Bile acid that protects liver mitochondria, enhances bile flow, and may aid in cellular repair

Q: How is this different from a basic liver support product?

A: Most liver formulas rely on just milk thistle or NAC. This product adds TUDCA, Setria® glutathione, and Katuki, ingredients that go beyond detox to support mitochondrial integrity, bile acid homeostasis, and intracellular antioxidant defense.

Q: When and how should I take it?

A: Take 4 vegetable capsules daily, ideally with a meal containing some dietary fat to enhance bile-related ingredient absorption. Can be taken in a single dose or split into 2 capsules twice daily.

Q: Who is this best for?

A: This is ideal for those who:

·       Regularly use medications, alcohol, or supplements processed through the liver

·       Are exposed to high levels of oxidative stress or toxins

·       Want to support bile flow, digestion, and systemic inflammation

·       Use TUDCA for liver, gallbladder, or mitochondrial health

·       Seek a broad-spectrum detox solution beyond just phase I/II clearance