Nattokinase (from Bacillus subtilis var. natto) (12,000 FU) – 600mg
A fibrinolytic enzyme derived from fermented soybeans (natto) known for cardiovascular and circulatory support.
- Supports healthy blood flow by promoting fibrin breakdown
- May help maintain normal blood pressure
- Aids in reducing blood viscosity and clot formation risk
- Contributes to vascular elasticity and endothelial function
- Supports overall cardiovascular health and circulation
- Above 10,000 FU is it shown to possess antiatherosclerotic and lipid-lowering effects and reduces the carotid artery thickness.
Synergy: Complements AmealPeptide® and Grape Seed Extract for vascular relaxation and circulation.
- Chen H, et al. Front Cardiovasc Med. 2022 Aug 22;9:964977.
- Hsia CH et al. Med Sci Monit. 2009;15(3):CR97–CR102.
- Kurosawa Y et al. Nat Med. 1995;49:379–383.
- Sumi H et al. Acta Haematol. 1987;78(3):180–183.
AmealPeptide® - 508mg
A clinically studied peptide complex from casein hydrolysate shown to support healthy blood pressure.
- Inhibits angiotensin-converting enzyme (ACE) to promote vasodilation
- Helps maintain healthy systolic and diastolic blood pressure
- Supports vascular relaxation and endothelial function
- May reduce arterial stiffness over time
- Promotes overall cardiovascular wellness
Synergy: Pairs with Nattokinase and Astragalus to support blood pressure and vascular integrity.
- Seppo L et al. Am J Clin Nutr. 2003;77(2):326–330.
- Yoshizawa M et al. J Nutr. 2000;130(4):779–782.
- Hata Y et al. Am J Clin Nutr. 1996;64(5):767–771.
Astragalus (Astragalus membranaceus) Powder (Root) (std. min. 5% yielding 25 mg Astragalosides) – 500mg
A traditional adaptogenic herb used to support kidney health and immune function.
- Promotes kidney function and glomerular filtration
- Supports endothelial integrity and vascular tone
- Provides antioxidant protection against oxidative damage
- May help regulate inflammatory pathways
- Enhances resilience to physiological stress
Synergy: Acts synergistically with Moringa and Andrographis to protect renal tissues and circulation.
- Ren S et al. Phytother Res. 2013;27(8):1113–1120.
- Zhang WJ et al. Am J Chin Med. 2003;31(4):509–518.
- Zhang L et al. Phytother Res. 2019;33(6):1604–1616.
Goldenrod (Solidago virgaurea) Powder (Root) – 400mg
An herb traditionally used for urinary tract and kidney support.
- Supports healthy fluid balance and diuresis
- Promotes detoxification through urinary pathways
- Provides antioxidant compounds that protect renal cells
- May help relieve mild urinary discomfort
- Contributes to kidney cleansing and function
Synergy: Complements Astragalus and Moringa to support fluid regulation and renal health.
- Blumenthal M et al. The Complete German Commission E Monographs. 1998.
- ESCOP Monographs. European Scientific Cooperative on Phytotherapy. 2003.
- Khan S et al. J Ethnopharmacol. 2019;238:111829.
Andrographis (Andrographis paniculata) Extract (Herb) (10:1) – 300mg
A botanical extract with anti-inflammatory and immune-supportive properties.
- Reduces systemic inflammation that can impact vascular health
- Supports healthy immune responses
- Provides antioxidant defense against oxidative stress
- May protect endothelial cells and microcirculation
- Supports detoxification pathways
Synergy: Works with Astragalus and Moringa to support kidney and vascular health.
- Coon JT, Ernst E. Br J Gen Pract. 2004;54(503):911–914.
- Akbar S. Asian Pac J Trop Biomed. 2011;1(1):S1–S10.
- Burgos RA et al. Phytother Res. 2009;23(7):919–924.
Grape Seed (Vitis vinifera) Extract (Seed) (std. min. 95% Proanthocyanidins) – 200mg
A polyphenol-rich antioxidant extract supporting vascular and endothelial health.
- Promotes nitric oxide availability and vasodilation
- Helps maintain healthy blood pressure
- Reduces oxidative stress in blood vessels
- Supports capillary strength and microcirculation
- Contributes to kidney microvascular protection
Synergy: Synergistic with AmealPeptide® and Nattokinase for comprehensive vascular support.
- Belcaro G et al. Clin Appl Thromb Hemost. 2013;19(3):343–348.
- Bagchi D et al. Toxicol. 2000;148(2-3):187–197.
- Sivaprakasapillai B et al. Metabolism. 2009;58(12):1743–1746.
Moringa (Moringa oleifera) Extract (Leaf) (10:1) – 100mg
A nutrient-dense botanical with antioxidant, anti-inflammatory, and renal-supportive compounds.
- Provides quercetin, chlorogenic acid, and vitamins for antioxidant protection
- May support kidney filtration and detoxification
- Contributes to blood pressure regulation through vasodilatory effects
- Supports metabolic health and fluid balance
- Enhances overall resilience and wellness
Synergy: Pairs with Astragalus and Goldenrod to promote renal health and antioxidant defense.
- Fahey JW. Trees for Life J. 2005;1:5.
- Ghasi S et al. J Ethnopharmacol. 2000;69(1):21–25.
- Waterman C et al. Phytother Res. 2014;28(2):193–200.
Synergy Overview
Cardiovascular & Blood Pressure Support: Nattokinase, AmealPeptide®, and Grape Seed Extract work through complementary mechanisms—fibrinolysis, ACE inhibition, and enhanced nitric oxide—to maintain healthy circulation and optimal blood pressure.
Kidney Function & Detoxification: Astragalus, Goldenrod, Moringa, and Andrographis collectively support glomerular filtration, urinary flow, and renal antioxidant defense.
Vascular & Microcirculation Protection: Grape Seed, Astragalus, and Moringa provide polyphenols and saponins that help maintain capillary integrity and reduce oxidative damage to vessels.
Anti-Inflammatory Defense: Andrographis, Astragalus, and Moringa modulate systemic inflammation that can impact both kidney and cardiovascular health.