Nattokinase (from Bacillus subtilis var. natto) (12,000 FU) – 600mg

A fibrinolytic enzyme derived from fermented soybeans (natto) known for cardiovascular and circulatory support.

• Supports healthy blood flow by promoting fibrin breakdown
• May help maintain normal blood pressure
• Aids in reducing blood viscosity and clot formation risk
• Contributes to vascular elasticity and endothelial function
• Supports overall cardiovascular health and circulation
• Above 10,000 FU is it shown to possess antiatherosclerotic and lipid-lowering effects and reduces the carotid artery thickness.

Synergy: Complements AmealPeptide® and Grape Seed Extract for vascular relaxation and circulation.

• Chen H, et al. Front Cardiovasc Med. 2022 Aug 22;9:964977.  
• Hsia CH et al. Med Sci Monit. 2009;15(3):CR97–CR102.
• Kurosawa Y et al. Nat Med. 1995;49:379–383.
• Sumi H et al. Acta Haematol. 1987;78(3):180–183.

AmealPeptide® - 508mg

A clinically studied peptide complex from casein hydrolysate shown to support healthy blood pressure.

• Inhibits angiotensin-converting enzyme (ACE) to promote vasodilation
• Helps maintain healthy systolic and diastolic blood pressure
• Supports vascular relaxation and endothelial function
• May reduce arterial stiffness over time
• Promotes overall cardiovascular wellness

Synergy: Pairs with Nattokinase and Astragalus to support blood pressure and vascular integrity.

• Seppo L et al. Am J Clin Nutr. 2003;77(2):326–330.
• Yoshizawa M et al. J Nutr. 2000;130(4):779–782.
• Hata Y et al. Am J Clin Nutr. 1996;64(5):767–771.

Astragalus (Astragalus membranaceus) Powder (Root) (std. min. 5% yielding 25 mg Astragalosides) – 500mg

A traditional adaptogenic herb used to support kidney health and immune function.

• Promotes kidney function and glomerular filtration
• Supports endothelial integrity and vascular tone
• Provides antioxidant protection against oxidative damage
• May help regulate inflammatory pathways
• Enhances resilience to physiological stress

Synergy: Acts synergistically with Moringa and Andrographis to protect renal tissues and circulation.

• Ren S et al. Phytother Res. 2013;27(8):1113–1120.
• Zhang WJ et al. Am J Chin Med. 2003;31(4):509–518.
• Zhang L et al. Phytother Res. 2019;33(6):1604–1616.

Goldenrod (Solidago virgaurea) Powder (Root) – 400mg

An herb traditionally used for urinary tract and kidney support.

• Supports healthy fluid balance and diuresis
• Promotes detoxification through urinary pathways
• Provides antioxidant compounds that protect renal cells
• May help relieve mild urinary discomfort
• Contributes to kidney cleansing and function

Synergy: Complements Astragalus and Moringa to support fluid regulation and renal health.

• Blumenthal M et al. The Complete German Commission E Monographs. 1998.
• ESCOP Monographs. European Scientific Cooperative on Phytotherapy. 2003.
• Khan S et al. J Ethnopharmacol. 2019;238:111829.

Andrographis (Andrographis paniculata) Extract (Herb) (10:1) – 300mg

A botanical extract with anti-inflammatory and immune-supportive properties.

• Reduces systemic inflammation that can impact vascular health
• Supports healthy immune responses
• Provides antioxidant defense against oxidative stress
• May protect endothelial cells and microcirculation
• Supports detoxification pathways

Synergy: Works with Astragalus and Moringa to support kidney and vascular health.

• Coon JT, Ernst E. Br J Gen Pract. 2004;54(503):911–914.
• Akbar S. Asian Pac J Trop Biomed. 2011;1(1):S1–S10.
• Burgos RA et al. Phytother Res. 2009;23(7):919–924.

Grape Seed (Vitis vinifera) Extract (Seed) (std. min. 95% Proanthocyanidins) – 200mg

A polyphenol-rich antioxidant extract supporting vascular and endothelial health.

• Promotes nitric oxide availability and vasodilation
• Helps maintain healthy blood pressure
• Reduces oxidative stress in blood vessels
• Supports capillary strength and microcirculation
• Contributes to kidney microvascular protection

Synergy: Synergistic with AmealPeptide® and Nattokinase for comprehensive vascular support.

• Belcaro G et al. Clin Appl Thromb Hemost. 2013;19(3):343–348.
• Bagchi D et al. Toxicol. 2000;148(2-3):187–197.
• Sivaprakasapillai B et al. Metabolism. 2009;58(12):1743–1746.

Moringa (Moringa oleifera) Extract (Leaf) (10:1) – 100mg

A nutrient-dense botanical with antioxidant, anti-inflammatory, and renal-supportive compounds.

• Provides quercetin, chlorogenic acid, and vitamins for antioxidant protection
• May support kidney filtration and detoxification
• Contributes to blood pressure regulation through vasodilatory effects
• Supports metabolic health and fluid balance
• Enhances overall resilience and wellness

Synergy: Pairs with Astragalus and Goldenrod to promote renal health and antioxidant defense.

• Fahey JW. Trees for Life J. 2005;1:5.
• Ghasi S et al. J Ethnopharmacol. 2000;69(1):21–25.
• Waterman C et al. Phytother Res. 2014;28(2):193–200.

Synergy Overview

Cardiovascular & Blood Pressure Support: Nattokinase, AmealPeptide®, and Grape Seed Extract work through complementary mechanisms—fibrinolysis, ACE inhibition, and enhanced nitric oxide—to maintain healthy circulation and optimal blood pressure.

Kidney Function & Detoxification: Astragalus, Goldenrod, Moringa, and Andrographis collectively support glomerular filtration, urinary flow, and renal antioxidant defense.

Vascular & Microcirculation Protection: Grape Seed, Astragalus, and Moringa provide polyphenols and saponins that help maintain capillary integrity and reduce oxidative damage to vessels.

Anti-Inflammatory Defense: Andrographis, Astragalus, and Moringa modulate systemic inflammation that can impact both kidney and cardiovascular health.