Vitamin K2 (as Menaquinone-7 / MK-7) – 120mcg (100%)

A fat-soluble vitamin critical for calcium metabolism and cardiovascular health.

• Activates matrix Gla-protein (MGP) to prevent arterial calcification
• Supports bone mineralization and density
• Helps maintain healthy vascular elasticity
• May contribute to reduction of arterial stiffness
• Enhances synergistic function with CoQ10 for cardiovascular support

Synergy: Combines with CoQ10 and Arjuna to promote vascular flexibility and arterial health.

• Theuwissen E et al. Thromb Haemost. 2015;113(6):1135–1144.
• Geleijnse JM et al. J Nutr. 2004;134(11):3100–3105.
• Brandenburg VM et al. Kidney Int. 2010;78(12):1119–1131.

 

Arjuna (Terminalia arjuna) Extract (Bark) (std. min. 20% Polyphenols) – 1,000mg

A cardiotonic botanical traditionally used in Ayurveda for heart function and circulation.

• Enhances left ventricular function and cardiac output
• Provides antioxidant polyphenols protecting myocardial tissue
• Supports endothelial integrity and nitric oxide production
• Helps maintain healthy lipid profiles
• May reduce stress-induced cardiovascular strain

Synergy: Pairs with Hawthorne and Resveratrol to support vascular function and antioxidant defense.

• Dwivedi S. J Ethnopharmacol. 2007;114(2):114–129.
• Bharani A et al. Int J Cardiol. 1995;49(3):191–199.
• Ram A et al. J Ethnopharmacol. 1997;55(3):165–169.

 

CardioAid® Plant Sterol Esters (std. min. 95% Plant Sterols) – 800mg

A clinically studied blend of plant sterols supporting healthy cholesterol levels.

• Reduces absorption of dietary cholesterol in the intestine
• May lower LDL-C by 5–15% with consistent use
• Supports maintenance of healthy lipid profiles
• Provides cardioprotective metabolic benefits
• Contributes to overall cardiovascular risk reduction

Synergy: Combines effectively with Red Yeast Rice to optimize lipid balance.

• Katan MB et al. Mayo Clin Proc. 2003;78(8):965–978.
• Demonty I et al. J Nutr. 2009;139(2):271–284.
• AbuMweis SS et al. Nutr Rev. 2008;66(6):348–360.

 

Red Yeast Rice (Monascus purpureus) Powder (Grain) – 600mg

A fermented rice product naturally containing monacolins that lower cholesterol levels.

• Supports reduction of LDL cholesterol and total cholesterol
• May improve triglyceride profiles
• Contributes antioxidant compounds including monascin and ankaflavin
• Supports endothelial function and vascular health
• Provides metabolic support for lipid regulation

Synergy: Works with CardioAid® and Citrus Bergamot to support comprehensive lipid management.

• Li YG et al. Chin Med. 2014;9:31.
• Heber D et al. Am J Clin Nutr. 1999;69(2):231–236.
• Cicero AF et al. Nutr Res. 2016;36(6):556–565.

 

Hawthorne (Crataegus pinnatifida) Extract (Berries) – 550mg

A heart-supportive botanical traditionally used to promote circulation and cardiac function.

• Enhances coronary blood flow and oxygen utilization
• Supports healthy blood pressure
• Provides flavonoids and oligomeric procyanidins for antioxidant protection
• May reduce mild symptoms of heart failure
• Promotes vascular relaxation and endothelial balance

Synergy: Acts synergistically with Arjuna and CoQ10 to promote cardiac efficiency.

• Pittler MH et al. Cochrane Database Syst Rev. 2008;(1):CD005312.
• Tauchert M. Herz. 2005;30(8):683–692.
• Chang Q et al. J Agric Food Chem. 2002;50(13):3785–3789.

 

Citrus Bergamot (Citrus bergamia) Extract (Fruit) (5:1) – 500mg

A polyphenol-rich citrus extract shown to support lipid and metabolic health.

• Helps lower LDL-C, total cholesterol, and triglycerides
• Increases HDL-C levels
• Provides flavonoids with antioxidant properties
• Supports endothelial function and vascular health
• May help maintain balanced blood glucose

Synergy: Complements Red Yeast Rice and Plant Sterols for lipid management.

• Mollace V et al. Fitoterapia. 2011;82(3):309–316.
• Gliozzi M et al. Crit Rev Food Sci Nutr. 2019;59(4):529–541.
• Raimondo S et al. Phytother Res. 2020;34(9):2210–2221.

 

Garlic (Allium sativum) Extract (Bulb) – 250mg

A time-tested botanical supporting cardiovascular and metabolic health.

• Supports reduction of total and LDL cholesterol
• Promotes healthy blood pressure through vasodilatory effects
• Provides sulfur compounds with antioxidant activity
• Supports immune health and resilience
• May improve endothelial function

Synergy: Works with Olive and Hawthorne for comprehensive vascular and metabolic support.

• Ried K et al. J Nutr. 2016;146(2):389S–396S.
• Ackermann RT et al. Ann Intern Med. 2001;135(4):277–287.
• Reinhart KM et al. Ann Pharmacother. 2008;42(12):1766–1776.

 

Olive (Olea europaea) Extract (Leaf) (std. min. 20% Oleuropein) – 200mg

A Mediterranean botanical extract rich in oleuropein, with cardiometabolic benefits.

• Supports healthy blood pressure and arterial function
• Provides potent antioxidant and anti-inflammatory compounds
• Contributes to balanced lipid profiles=
• Supports endothelial nitric oxide balance
• Enhances resilience against oxidative stress

Synergy: Complements Garlic and Resveratrol to support vascular tone and oxidative defense.

• Lockyer S et al. Nutrients. 2017;9(8):677.
• Susalit E et al. Phytomedicine. 2011;18(4):251–258.
• de Bock M et al. Eur J Nutr. 2013;52(6):1607–1617.

 

Resveratrol (from Japanese Knotweed) (Polygonum cuspidatum) Extract (Root) (std. min. 98%) – 150mg

A polyphenol compound known for vascular protection and anti-aging properties.

• Promotes nitric oxide production for vascular relaxation
• Provides antioxidant protection to endothelial tissues=
• May support healthy lipid metabolism
• Contributes to glucose regulation and metabolic balance
• Protects mitochondrial function

Synergy: Acts with Olive, Garlic, and Hawthorne for comprehensive cardioprotective support.

• Baur JA et al. Nat Rev Drug Discov. 2006;5(6):493–506.
• Magyar K et al. Curr Med Chem. 2012;19(25):4179–4195.
• Tomé-Carneiro J et al. Ann N Y Acad Sci. 2013;1290:52–60.

 

Coenzyme Q10 (Ubiquinone) – 100mg

A vital mitochondrial nutrient supporting energy production and cardiovascular health.

• Supports ATP generation in cardiac and skeletal muscle
• Provides antioxidant protection to lipids and cell membranes
• May help reduce oxidative stress associated with statin use
• Supports endothelial nitric oxide activity
• Enhances energy, vitality, and cardiovascular resilience

Synergy: Complements Vitamin K2 and Arjuna to protect cardiac function and vascular health.

• Mortensen SA et al. J Am Coll Cardiol. 2014;64(18):1888–1890.
• Rosenfeldt F et al. Biofactors. 2003;18(1-4):91–100.
• Littarru GP, Tiano L. Pharmacol Ther. 2007;133(2):92–106.

 

Synergy Overview

Lipid Management & Metabolic Support: Red Yeast Rice, CardioAid®, Citrus Bergamot, and Garlic target complementary pathways to promote healthy cholesterol and triglycerides.

Vascular Health & Circulation: Arjuna, Hawthorne, Olive, and Resveratrol work in concert to improve endothelial function and arterial flexibility.

Oxidative Stress & Mitochondrial Protection: CoQ10, Resveratrol, Olive, and Hawthorne provide powerful antioxidant defense for heart and vessel health.

Blood Pressure Balance: Garlic, Olive, Arjuna, and Hawthorne help support healthy systolic and diastolic pressure.