Morosil® Solid Extract of Sicilian Red Orange (Citrus sinensis) – 400 mg
A standardized Moro blood orange extract rich in anthocyanins and citrus polyphenols, clinically studied for supporting body composition and metabolic health.
- Supports healthy reductions in body weight and body fat
- May help reduce waist and hip circumference
- Supports healthy lipid and adipose tissue metabolism
- Provides antioxidant protection against metabolic oxidative stress
- Complements diet and exercise during weight-management programs
Synergy: Works with Dihydroberberine, Banaba, and Gymnema to combine body-composition support with enhanced glucose management. Complements Eriomin® and DHM for broader metabolic and antioxidant support.
- Cardile V et al. Nat Prod Res. 2015;29(23):2250–2254
- Briskey D et al. Nutrients. 2022;14(3):427
- Campos CMG et al. Clin Nutr ESPEN. 2025
- Salamone F et al. World J Gastroenterol. 2012;18(47):6874–6881
Vine Tea (Ampelopsis grossedentata) Extract (98% Dihydromyricetin) – 300 mg
A highly concentrated source of dihydromyricetin (DHM), a flavonoid studied for supporting insulin sensitivity, glucose metabolism, lipid metabolism, and healthy liver function.
- Supports healthy insulin sensitivity and glucose regulation
- Promotes healthy lipid and triglyceride metabolism
- Supports liver function during metabolic stress
- Helps regulate oxidative and inflammatory pathways
- May improve overall metabolic flexibility and nutrient handling
Synergy: Works with Dihydroberberine and Banaba to support insulin sensitivity through complementary pathways. Combines with Eriomin® and Bitter Melon for comprehensive glucose and metabolic support.
- Chen S et al. Pharmacol Res. 2015;99:74–81
- Ran L et al. J Nutr Sci Vitaminol. 2019;65(1):42–47
- Li H et al. Oxid Med Cell Longev. 2017;2017:1053617
- He J et al. Diabetes Metab Syndr Obes. 2019;12:1643–1653
Bitter Melon (Momordica charantia) Extract – 250 mg
A traditional metabolic herb containing bioactive compounds that support glucose utilization, insulin signaling, and carbohydrate metabolism.
- Supports healthy fasting and post-meal blood glucose
- Promotes peripheral glucose uptake and utilization
- Supports healthy insulin sensitivity
- Helps regulate carbohydrate and lipid metabolism
- May support pancreatic and metabolic function
Synergy: Combines with Gymnema and Banaba for comprehensive post-meal glucose control. Works with Dihydroberberine to target glucose regulation through multiple complementary mechanisms. Clinical findings are promising, although results across trials remain somewhat variable.
- Zhang X et al. Heliyon. 2024;10:e31126
- Yang YS et al. Nutrients. 2022;14(3):672
- Peter EL et al. J Ethnopharmacol. 2019;231:311–324
- Laczkó-Zöld E et al. Front Nutr. 2024;10:1200801
- Mkhize SAL et al. Diabetes Epidemiol Manag. 2025
Gymnema (Gymnema sylvestre) Extract (25% Gymnemic Acids) – 250 mg
An Ayurvedic botanical traditionally called the “sugar destroyer,” studied for supporting glucose regulation and reducing the desire for sweet foods.
- Supports healthy fasting and post-meal glucose levels
- May reduce the perception and appeal of sweet foods
- Supports insulin secretion and insulin sensitivity
- Helps regulate carbohydrate utilization
- May support healthy lipid levels alongside glucose control
Synergy: Pairs with Bitter Melon and Banaba for comprehensive carbohydrate management. Works with Dihydroberberine to reinforce insulin sensitivity while providing additional support for sugar cravings and dietary adherence.
- Devangan S et al. Phytother Res. 2021;35(12):6802–6812
- Turner S et al. Nutrients. 2020;12(4):1046
- Turner S et al. Nutrients. 2022;14(24):5226
- Baskaran K et al. J Ethnopharmacol. 1990;30(3):295–300
- Shanmugasundaram ERB et al. J Ethnopharmacol. 1990;30(3):281–294
Banaba (Lagerstroemia speciosa) Extract (1% Corosolic Acid) – 200 mg
A traditional Southeast Asian botanical standardized for corosolic acid, a triterpenoid studied for enhancing cellular glucose uptake and supporting insulin sensitivity.
- Supports glucose uptake into skeletal muscle and other tissues
- Promotes healthy post-meal blood glucose levels
- Supports insulin sensitivity and glucose transport
- Helps maintain healthy carbohydrate metabolism
- May support healthy lipid metabolism and nutrient partitioning
Synergy: Works with Dihydroberberine to enhance peripheral glucose disposal. Complements Gymnema and Bitter Melon for multi-pathway control of the post-meal glycemic response.
- Stohs SJ et al. Phytother Res. 2012;26(3):317–324
- Miura T et al. Evid Based Complement Alternat Med. 2012;2012:871495
- Judy WV et al. J Ethnopharmacol. 2003;87(1):115–117
- Fukushima M et al. Diabetes Res Clin Pract. 2006;73(2):174–177
Fenugreek (Trigonella foenum-graecum) Extract (50% Saponins) – 200 mg
A traditional metabolic herb rich in steroidal saponins and other bioactive compounds studied for supporting glucose metabolism, insulin sensitivity, and healthy lipid levels.
- Supports healthy fasting and post-meal glucose
- Promotes insulin sensitivity and glucose utilization
- Supports healthy carbohydrate metabolism
- May help maintain healthy triglyceride and cholesterol levels
- Supports metabolic health during higher carbohydrate intake
Synergy: Complements Gymnema and Bitter Melon for carbohydrate management. Works alongside Dihydroberberine and Banaba to reinforce insulin sensitivity and glucose disposal.
- Neelakantan N et al. Nutr J. 2014;13:7
- Kim J et al. Int J Mol Sci. 2023;24(18):13999
- Vajdi M et al. BMC Complement Med Ther. 2024
- Fakhr L et al. Pharmacol Res. 2023;187:106594
- Basch E et al. Altern Med Rev. 2003;8(1):20–27
Dihydroberberine (DHB) – 150 mg
A reduced metabolite of berberine designed to achieve substantially greater systemic berberine exposure at lower oral doses than conventional berberine. Human pharmacokinetic research supports markedly greater berberine appearance in blood following DHB administration.
- Supports healthy glucose metabolism and insulin sensitivity
- Promotes activation of metabolic pathways involved in glucose and lipid regulation
- Supports healthy post-meal blood glucose
- Provides a highly bioavailable alternative to conventional berberine
- May provide metabolic benefits at substantially lower doses than standard berberine
Synergy: Serves as a central glucose-management component alongside Banaba, Gymnema, and Bitter Melon. Complements DHM and Eriomin® for broader insulin-sensitivity and metabolic support.
- Moon JM et al. Nutrients. 2022;14(1):124
- Chang C et al. Int J Mol Sci. 2024;25(11):5625
- Buchanan B et al. PLoS One. 2018;13(3):e0194979
- Turner N et al. Diabetes. 2008;57(5):1414–1418
Eriomin® Citrus Bioflavonoid Complex (≥80% Eriocitrin) – 100 mg
A standardized lemon-derived citrus flavonoid complex rich in eriocitrin, clinically studied for glucose control, insulin sensitivity, GLP-1 activity, and inflammatory balance.
- Supports healthy fasting blood glucose and insulin sensitivity
- May increase endogenous GLP-1 activity
- Supports healthy glucagon regulation
- Helps reduce oxidative and inflammatory stress associated with metabolic dysfunction
- Supports glucose tolerance and overall metabolic health
Synergy: Complements Dihydroberberine, Banaba, and Gymnema for comprehensive glucose regulation. Pairs particularly well with DHM to support insulin sensitivity, inflammatory balance, and metabolic signaling.
- Ribeiro CB et al. Phytother Res. 2019;33(7):1921–1933
- Ramos FMM et al. J Med Food. 2023;26(1):24–32
- Ramos FMM et al. Phytother Res. 2023
- Cesar TB et al. Food Funct. 2010;1(2):214–218