ALPHAGEN - Ingredient write-ups

Citrulline Malate

  • L-Citrulline is an amino acid that is more effective at increasing L-Arginine levels in the body than L-Arginine supplementation. Malate (or Malic Acid) is a Kreb's cycle intermediate involved in energy metabolism. Typically they are combined in a 2:1 ratio as L-Citrulline DL-Malate.
  • Increases nitric oxide (NO) metabolism, resulting in greater blood flow and “pump”. Used to alleviate erectile dysfunction caused by high blood pressure.
  • Improves metabolite recycling processes, reduces fatigue and improves endurance for both aerobic and anaerobic exercise.
  • Common dosing is 6,000-8,000mg of L-Citrulline DL-Malate 2:1.
  • ALPHAGEN contains 8,000mg L-Citrulline DL-Malate 2:1 per 1 scoop.

Creatine Monohydrate

  • The most widely studied and supported form of creatine on the market.
  • Rapidly replenishes cellular energy (adenosine triphosphate; ATP) for increased strength, power and endurance.
  • Increases intracellular fluid for enhanced hydration and muscle protein synthesis.
  • Possesses neuroprotective and cardioprotective properties.
  • Creatine should be dosed at 0.03 g/kg/day. For a 180 lb (82 kg) person, this translates to approximately 2.5 g/day.
  • ALPHAGEN contains 5g creatine monohydrate per 1 scoop. 

Beta-alanine

  • The rate limiting amino acid in carnosine synthesis (when combined with histidine in the body, which is readily available).
  • Carnosine acts as a buffer of acid in muscles, increasing physical performance and delaying fatigue.
  • Beta-alanine can cause slight tingling of the extremities called paresthesia, which is a harmless side effect that quickly dissipates.
  • Most common dosing is 1.6-3.2g/day, either all at once or in divided doses.
  • ALPHAGEN contains 3.2g beta-alanine per 1 scoop.

L-Tyrosine

  • A nonessential amino acid that is used to make the catecholamine neurotransmitters dopamine, norepinephrine, and epinephrine (adrenaline).
  • Acts as an anti-stress compound for acute stressors such as strenuous exercise.While L-tyrosine is less water soluble than other forms of tyrosine (N-acetyl tyrosine, for example), it is more bioavailable in the body and thus raises plasma tyrosine levels up to 10x more than other forms of tyrosine.
  • Tyrosine is commonly dosed between 500-2,000mg up to 60 minutes prior to activity.
  • ALPHAGEN contains a 2,000mg L-tyrosine per 1 scoop.

DMAE Bitartrate

  • Dimethylaminoethanol bitartrate (DMAE) is a nootropic (brain health and enhancement) compound which increases the neurotransmitter acetylcholine in the brain.
  • DMAE is not to be confused with the stimulants DMAA/DMHA or the DHEA hormones and their respective derivatives. DMAE is safe and not banned by athletic organizations. 
  • Used extensively in treating cognitive decline in populations such as the aging and those with Alzheimer’s by increasing blood and oxygen flow as well as glucose uptake in the brain.
  • Enhances cognition, focus and memory.
  • DMAE is commonly dosed in the range of 300-1,500mg/day and is effective at lower dosing when paired with Huperzine A.
  • ALPHAGEN contains 750mg DMAE bitartrate per 1 scoop.

Mucuna Pruriens

  • Derived from the velvet bean plant and is a rich source of L-DOPA, the precursor to dopamine and eventually adrenaline.
  • Dopamine plays a major role in reward-motivated behavior, similar to (albeit to a lesser degree) drugs such as cocaine, which make the user feel energetic, happy, and increases their ability to undertake stressful tasks. Dopamine is also involved in motor control.
  • L-DOPA has been shown to increase circulating dopamine levels in doses up to 735mg/day.
  • ALPHAGEN contains 750mg mucuna pruriens (98% L-DOPA) per scoop, providing 735mg per 1 scoop. 

AlphaSize®

  • AlphaSize® Alpha-Glyceryl Phosphoryl Choline (A-GPC) is recognized as the "premier" choline donor, especially compared to other forms of choline that offer reduced bioavailability.
  • Promotes formation of acetylcholine (AC), a vital neurotransmitter compound involved in all key brain functions and mental sharpness.
  • Improvement in key brain functions, including memory, concentration, learning, recall, and focus.
  • Optimizes muscular power output, sharpens agility, and also delays mental fatigue due motor unit activation of muscle fibers and subsequent muscle contraction, as well as its mental sharpness benefits.
  • ALPHAGEN contains 600mg patented and trademarked AlphaSize® (50% yielding 300mg AlphaGPC) per 1 scoop.

    TeaCrine®

    • Theacrine (as TeaCrine™) is an alkaloid structurally similar to caffeine and activates similar signaling pathways. Evidence also suggests less tolerance with theacrine compared to caffeine.
    • Similar to Dynamine but more gradual onset and longer lasting.
    • Boosts mental and physical energy without jitters or irritability.
    • Supports a positive mood, increases motivation to exercise, and improves perceived focus and concentration. Does not lead to rapid tolerance or habituation.
    • ALPHAGEN contains 100mg Theacrine (from 250mg non-bitter TeaCrine™) per 1 scoop. 

    Dynamine™

    • Methylliberine (as Dynamine™) is an alkaloid structurally similar to caffeine and activates similar signaling pathways. Evidence also suggests less tolerance with methylliberine compared to caffeine.
    • Similar to Teacrine but shorter onset and fast acting. 
    • Boosts mental and physical energy without jitters or irritability.
    • Supports a positive mood, increases motivation to exercise, and improves perceived focus and concentration. Does not lead to rapid tolerance or habituation.
    • ALPHAGEN contains 100mg Methylliberine (from 250mg non-bitter Dynamine™) per 1 scoop.

    Caffeine

    • Caffeine is often used to improve physical strength and endurance as well as provide mental stimulation.
    • Widely studied for safety and efficacy and most people tolerate it well on a spectrum of dosing. Caution should always be used and dosing should be slowly increased over time as needed for desired effects.
    • Caffeine’s half-life is 2.5-4.5 hours so novel, time-released forms of caffeine are generally not necessary.
    • Dosing should be approximately 200mg for fat-burning and 4-6mg/kg BW acutely for increasing strength and power output. For a 180 lb (82 kg) person, this translates to approximately 330-500mg prior to exercise.
    • ALPHAGEN contains 200mg caffeine anhydrous per 1 scoop, coupled with 100mg Theacrine and 100mg Methylliberine for a total of 400mg caffeine-like compounds.  

    Eria Jarensis

    • Eria Jarensis Extract (N-Phenethyl Dimethylamine Citrate) is a rich source amines (such as Phenylethylamine, or PEA) that acts as a neurotransmitter and has positive effects on many of the “happy hormones” such as dopamine and serotonin.
    • PEA is rapidly broken down by the MAO-B enzyme whereas the effects of Eria Jarensis are more prolonged.
    • Is lipophilic (able to dissolve in fats) and is able to cross the blood-brain barrier more easily than traditional PEA derivatives.
    • Has been used in the food supply and is GRAS Status (is Generally Recognized as Safe) as a food additive.
    • Shown to elicit anti-depressant actions during exercise, and mood enhancing and energetic effects before traditional stimulants such as caffeine.
    • ALPHAGEN contains 200mg Eria Jarensis Extract per serving.

     

    Theobromine

    • The primary “feel good” compound in chocolate, theobromine is a cocoa extract that may provide cardiovascular and cognitive benefits through improved blood flow and antioxidant effects as well as energy production.
    • Increases exercise performance, muscle contractile force, blood flow, alertness, mood enhancement, and metabolic rate.
    • Theobromine is commonly dosed between 50-200mg prior to activity.
    • ALPHAGEN contains 200mg Theobromine 99% per 1 scoop.  

    L-Theanine

    • The relaxing amino acid found in tea, theanine promotes relaxation without sedation; it helps you stay calm without making you tired or drowsy.
    • Reduces stress and improves attention.
    • Theanine helps take off the ‘edge’ of many stimulants, and a synergistic effect is seen when coupled with caffeine in promoting cognition and attention.
    • Theanine is commonly dosed between 100-200mg prior to activity, or synergistically in combination with caffeine (and caffeine-like compounds). 
    • ALPHAGEN contains 200mg L-theanine per 1 scoop. 

       Synephrine HCL

      • A beta-agonist similar to ephedrine, albeit less potent.
      • Increases metabolic rate and fat-burning and shows synergism with caffeine.
      • Synephrine is not banned by WADA (World Anti-Doping Agency), has failed to cause false positive drug testing for amphetamines, and has been shown to be safe and free of most adverse side effects.
      • 50mg synephrine when taken by healthy subjects at rest has been shown to increase caloric expenditure by 65kcal with no significant influence blood pressure or heart rate.
      • Synephrine is commonly dosed at 10-20mg 3 x day, or 50mg acutely.
      • ALPHAGEN contains 50mg synephrine HCL per 1 scoop. 

      AstraGin®

      • AstraGin® is a patented blend of highly purified saponins isolated from the Astragalus membranaceous and Panax notoginseng plant.
      • Shown to dramatically increase the absorption and bioavailability of a variety of nutrients, such as peptides, amino acids, glucose, vitamins and minerals, phytonutrients, and various sports nutrition supplements.
      • Supports the gut ecosystem by providing a favorable microbiome environment.
      • Enhances the immune system.
      • Recommended daily dose is 50mg per day.
      • ALPHAGEN contains 50mg AstraGin® per serving.

            Bioperine®

            • Bioperine® is the trademarked version of piperine, a black pepper extract that increases the absorption of various nutrients such as curcumin (up to 2,000% in humans) as well as inhibits the breakdown of fat-burning compounds such as caffeine and the catecholamines, prolonging the effects of preworkout stimulants and increasing their bioavailability.
            • Piperine also reduces LDL cholesterol and plasma lipids while elevating HDL cholesterol and the thyroid hormones.
            • Common dosing is 5-10mg for preworkout supplements and 20mg for curcumin containing products such as MorphoPRIME and ORTHOGEN. 
            • ALPHAGEN contains 10mg Bioperine® per 1 scoop.

            Huperzine A

            • A nootropic molecule that inhibits the enzyme that breaks down the neurotransmitter acetylcholine. Huperzine makes choline sources work better for longer.
            • Huperzine A is shown to work better than Rx drugs for this purpose and is also neuroprotective.
            • Effective dosing is 50-300mcg, but because the long half-life of huperzine, consuming the top end of the dosing (300mcg) daily may cause huperzine to build up in the system, so a more moderate dose may be safer and just as effective.
            • ALPHAGEN contains 200mcg huperzine A per 1 scoop.

             

             

             

             

            Warnings: Not intended for use by persons under the age of 18. If you are pregnant or nursing or are taking any prescription medications, consult your health care professional before using this or any other dietary supplement product. Contact your health care professional before using this or any other dietary supplement product. Immediately discontinue use and consult your doctor if any adverse reactions occur. KEEP OUT OF REACH OF CHILDREN. STORE IN A COOL, DRY PLACE AND AVOID EXCESSIVE HEAT.

            ALLERGEN INFORMATION: This product is manufactured in a facility that processes other products which may contain soy, dairy, wheat, tree nuts, shellfish, fish, peanuts, and eggs.

            *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.