
CALM: STRESS + MOOD SUPPORT
Stress + Fatigue Support • Rest + Relaxation • Mental Well-Being
CALM is a daily formula designed to help you manage stress, fight fatigue, and stay mentally locked in. With clinically studied adaptogens and mood-support compounds, CALM promotes neurotransmitter balance, emotional control, and relaxation. Whether you're deep into a training block or just navigating a high-stress lifestyle, CALM helps restore your edge.
Key Benefits:
- Helps control cortisol, the primary stress hormone
- Promotes a steady, centered emotional state throughout daily challenges
- Helps support a balanced stress response for calmer decision-making
- Encourages a relaxed, non-stimulated sense of clarity
- Supports mood elevation through multiple neuromodulatory pathways
- Helps smooth out irritability and emotional reactivity
- Enhances adaptive resilience to mental and physical stressors
- Supports a soothed nervous system for easier unwinding
- Promotes neurotransmitter balance involved in calm focus and emotional regulation
- Encourages a more positive, uplifted outlook during high-pressure periods
- Complements daily routines, evening routines, or sleep-support stacks

Vitamin D3 (Cholecalciferol, vegan) – 20 mcg
A fat-soluble vitamin critical for calcium metabolism, immune regulation, neuromuscular function, and mood stability.
- Enhances calcium absorption and bone mineral density.
- Regulates innate and adaptive immune responses.
- Supports mood and cognitive performance via VDR pathways.
- Contributes to muscle contraction and anti-inflammatory signaling.
- May reduce incidence of seasonal depression and fatigue.
Synergy: Works with magnesium, B vitamins, and Aquamin® minerals to regulate bone integrity, neurotransmission, and inflammation control.
- Holick MF. N Engl J Med. 2007;357(3):266–281.
- Gombart AF et al. Front Immunol. 2020;11:242.
- McCann JC, Ames BN. Mol Psychiatry. 2008;13(5):472–483.
- Heaney RP et al. Am J Clin Nutr. 2003;77(2):383–389.
Vitamin B3 (Niacinamide) – 16 mg
A water-soluble form of vitamin B₃ involved in redox cycling and mitochondrial NAD+/NADP+ production.
- Supports mitochondrial respiration and energy metabolism.
- Enhances DNA repair and antioxidant function.
- Promotes skin integrity and anti-inflammatory signaling.
- Regulates cholesterol and vascular health.
- Reduces oxidative stress and fatigue.
Synergy: Works with B6, folate, B12, and CoQ10 to promote NAD⁺ synthesis, redox balance, and ATP generation.
- Bogan KL, Brenner C. Annu Rev Nutr. 2008;28:115–130.
- Hikosaka K et al. J Nutr Sci Vitaminol. 2011;57(5):387–392.
- Kamanna VS, Ganji SH. J Nutr. 2007;137(9):2135–2140.
- Offermanns S. Br J Pharmacol. 2006;147 Suppl 1:S68–S76.
Vitamin B6 (Pyridoxal‑5′‑Phosphate) – 1.7 mg
The active coenzyme form of B6 essential for neurotransmitter synthesis and methylation pathways.
- Enables production of serotonin, dopamine, GABA, and norepinephrine.
- Supports homocysteine metabolism and cardiovascular health.
- Enhances immune function and protein metabolism.
- Helps regulate blood glucose and energy output.
- Modulates cognitive performance and mood.
Synergy: Collaborates with magnesium, folate, and B12 to optimize methylation and stress regulation.
- Dakshinamurti K. J Nutr. 1995;125(6):1511–1516.
- Ubbink JB et al. Clin Chem Lab Med. 1996;34(8):747–751.
- Shaheen S et al. Am J Clin Nutr. 1993;57(3):302–306.
- Paul L et al. Am J Clin Nutr. 2002;76(2):437–441.
Folate (as L‑5‑Methyltetrahydrofolate) – 400 mcg DFE
The bioactive form of folate involved in methylation, DNA synthesis, and neurological development.
- Supports methylation of neurotransmitters, DNA, and phospholipids.
- Reduces homocysteine and cardiovascular risk.
- Supports fetal neural development and fertility.
- Enhances cognitive function and emotional stability.
- Aids detoxification via one-carbon metabolism.
Synergy: Complements B6 and B12 to regulate methylation, neurotransmitter synthesis, and cardiovascular integrity.
- Bailey SW, Ayling JE. Clin Chem. 2009;55(11):1911–1923.
- Selhub J. J Nutr. 1999;129(9):1731–1736.
- Reynolds EH et al. Lancet. 1985;1(8431):862–864.
- Kennedy DO. Neuropsychobiology. 2016;73(2):89–95.
Vitamin B12 (Methylcobalamin) – 2.4 mcg
The methylated coenzyme form of B12 required for DNA synthesis, red blood cell production, and neurological repair.
- Regulates homocysteine and supports cardiovascular function.
- Supports myelin sheath repair and neurotransmitter balance.
- Prevents anemia and boosts mitochondrial energy.
- May enhance cognitive clarity and mood.
Synergy: Works alongside folate and B6 to regulate methylation, homocysteine, and neurological health.
- O’Leary F, Samman S. Int J Food Sci Nutr. 2010;61(6):588–599.
- Stabler SP. Annu Rev Med. 2013;64:59–73.
- Scalabrino G. J Neurol Sci. 2009;285(1–2):9–13.
- Stabler SP. Blood. 2013;121(18):3471–3480.
Pantothenic Acid – 5 mg
Vitamin B₅ precursor to coenzyme A (CoA), vital for energy, hormone synthesis, and fatty acid metabolism.
- Supports ATP synthesis and mitochondrial energy output.
- Aids production of cortisol, neurotransmitters, and acetylcholine.
- Helps reduce fatigue and improve physical resilience.
- Supports adrenal function and stress recovery.
Synergy: Enhances CoA and acetylation pathways alongside B3, B6, and magnesium.
- Smith CM. J Nutr. 1991;121(1):18–28.
- Tomono S et al. Nippon Yakurigaku Zasshi. 1995;105(4):265–271.
- Campbell SC et al. Am J Clin Nutr. 1993;58(4):528–534.
- Finglas PM et al. Pediatr Dermatol. 2000;17(6):463–469.
Magnesium (Aquamin® Mg Tg) – 42 mg
A highly bioavailable marine-derived form of magnesium that supports enzymatic, neuromuscular, and metabolic functions.
- Acts as cofactor in over 300 enzymatic reactions.
- Supports muscle function, neurotransmission, and stress recovery.
- Regulates sleep, blood sugar, and blood pressure.
- Aids bone density and inflammatory modulation.
Synergy: Pairs with vitamin D3, B-complex, and adaptogens to support calm focus, energy metabolism, and HPA balance.
- Firoz M, Graber M. ISRN Pharmacol. 2014;2014:494308.
- Tarleton EK et al. Nutrients. 2018;10(9):1176.
- de Baaij JH et al. Physiol Rev. 2015;95(1):1–46.
- Minton O et al. Sleep Med Rev. 2017;31:11–21.
Phosphatidylserine (50%) – 600 mg
A brain phospholipid that enhances memory, attention, and stress response regulation.
- Promotes memory, learning, and neural signaling.
- Reduces cortisol and stress-induced fatigue.
- Enhances focus, clarity, and attention span.
- Supports neuroprotection and HPA axis resilience.
Synergy: Amplifies cognitive and anti-stress effects of Ginseng, Rhodiola, and Theanine.
- Glade MJ, Smith K. Nutrition. 2015;31(6):781–785.
- Hellhammer J et al. Neuroendocrinol Lett. 2004;25(3):233–239.
- Jorissen BL et al. Nutr Neurosci. 2001;4(4):297–305.
- Crook TH et al. Neurology. 1991;41(5):644–649.
Magnolia (Magnolia officinalis) – 300 mg
A bark extract containing honokiol and magnolol with calming, antioxidant, and neuroprotective properties.
- Reduces anxiety and modulates cortisol.
- Improves sleep onset and quality.
- Protects brain cells from oxidative stress.
- May support microbiota and gut–brain communication.
Synergy: Combines with Theanine, Kanna, and Ashwagandha to improve mood and calmness.
- Kuribara H et al. J Ethnopharmacol. 1999;65(2):157–162.
- Chioca LR et al. Evid Based Complement Alternat Med. 2009;6(3):273–281.
- Kang SS et al. Int J Mol Sci. 2017;18(6):1298.
- Lee HJ et al. J Neurosci Res. 2011;89(10):1770–1781.
L-Theanine – 300 mg
A non-proteinogenic amino acid from green tea that promotes calm and alertness.
- Increases alpha brain wave activity.
- Enhances relaxation without sedation.
- Supports mood, sleep quality, and focus.
- May reduce stress-induced sympathetic activity.
Synergy: Works with Magnolia, Kanna, and PS for mood, relaxation, and cognitive support.
- Nobre AC et al. Brain Topogr. 2008;22(2):41–48.
- Kimura K et al. Biol Psychol. 2007;74(1):39–45.
- Lu K et al. Nutr Neurosci. 2004;7(4):177–182.
- Unno K et al. J Funct Foods. 2013;5(4):1238–1244.
Rhodiola (Rhodiola crenulata, 6% salidrosides) – 300 mg
A well-characterized adaptogen that enhances resilience to physical and mental stress.
- Boosts mental performance and cognitive endurance.
- Reduces fatigue and improves mood.
- Increases mitochondrial efficiency and oxygen utilization.
- Supports HPA axis and neuroprotection.
Synergy: Works with Ashwagandha, Reishi, and Schisandra for adaptogen synergy.
- Shevtsov VN et al. Planta Med. 2003;69(2):109–113.
- Olsson EM et al. Phytomedicine. 2009;16(4):298–310.
- Panossian A et al. Phytomedicine. 2008;15(1–2):84–91.
- Front Pharmacol. 2022;13:974775.
Reishi Mushroom (Ganoderma lucidum) – 250 mg
A medicinal mushroom containing triterpenoids and beta-glucans that modulate immunity and stress.
- Enhances immune surveillance and resilience.
- Reduces fatigue and anxiety.
- Supports anti-inflammatory and antioxidant activity.
- May aid sleep quality and liver protection.
Synergy: Blends with Rhodiola, Magnolia, and Schisandra to regulate immune and HPA activity.
- Gao Y et al. Pharmacol Ther. 2004;102(3):313–337.
- Boh B et al. Int J Med Mushrooms. 2007;9(4):297–310.
- Wachtel-Galor S et al. Altern Med Rev. 2004;9(2):166–176.
- Wasser SP. Appl Microbiol Biotechnol. 2011;89(5):1323–1332.
Schisandra chinensis – 250 mg
A traditional adaptogen rich in lignans with effects on stress resilience, liver detox, and mental performance.
- Improves endurance and cognitive function under stress.
- Supports liver detoxification and glutathione activity.
- Reduces anxiety and mental fatigue.
- Enhances learning and memory.
Synergy: Amplifies stress adaptation alongside Rhodiola, Reishi, and PS.
- Panossian A et al. Phytomedicine. 2008;15(1–2):91–99.
- Szolomicki S et al. Pharmacol Rep. 2000;52(2):123–130.
- Kimura Y et al. J Nat Med. 2005;59(3):249–257.
- Bok SH et al. J Nutr Biochem. 2001;12(12):636–640.
Ginseng (Panax ginseng) (7% ginsenosides) – 200 mg
A renowned adaptogen that improves physical and cognitive performance.
- Increases energy, stamina, and mitochondrial output.
- Enhances cognitive clarity and focus.
- Modulates stress and supports HPA axis.
- Boosts immune cell activity and cytokine balance.
Synergy: Pairs with B-complex, Rhodiola, and Reishi to support cognition and fatigue reduction.
- Reay JL et al. Psychopharmacology (Berl). 2005;179(4):644–651.
- Kennedy DO et al. Psychopharmacology (Berl). 2006;185(4):512–520.
- Scaglione F, Cattaneo G. Int J Immunopharmacol. 2001;23(6):307–314.
- Kim JH et al. J Ginseng Res. 2013;37(1):1–12.
Shoden® Ashwagandha (35% withanolides) – 120 mg
A potent adaptogen clinically validated to reduce cortisol and enhance stress tolerance.
- Lowers serum cortisol and perceived stress.
- Improves sleep, recovery, and resilience.
- Enhances mood, testosterone, and cognitive function.
- Supports immunity and thyroid function.
Synergy: Combines with Magnolia, Reishi, Rhodiola, and Schisandra to form a foundational adaptogen matrix.
- Wankhede S et al. J Int Soc Sports Nutr. 2015;12:43.
- Chandrasekhar K et al. Indian J Psychol Med. 2012;34(3):255–262.
- Lopresti AL et al. Cureus. 2019;11(5):e4787.
- Pratte MA et al. J Diet Suppl. 2014;11(2):153–170.
Kanna (Sceletium tortuosum) (0.5% alkaloids) – 50 mg
A South African botanical containing mesembrine alkaloids that act as serotonin reuptake inhibitors and PDE4 inhibitors.
- Improves mood, sociability, and resilience.
- Reduces anxiety and emotional reactivity.
- Enhances cognitive performance and alertness.
- Supports stress resilience via serotonergic modulation.
Synergy: Enhances mood benefits of PS, Magnolia, Theanine, and Saffron.
- Smith CA et al. J Ethnopharmacol. 2002;79(2):287–293.
- Harvey AL et al. Biochem Soc Trans. 2011;39(2):315–319.
- Jacobson AR et al. J Psychopharmacol. 2015;29(11):1194–1208.
- Terburg D et al. J Neurosci. 2013;33(9):3794–3800.
Saffron (Crocus sativus) (0.3% safranal) – 30 mg
A mood-supporting botanical with antidepressant and antioxidant effects.
- Reduces depressive symptoms and anxiety.
- Improves mood, sleep, and calm focus.
- Supports antioxidant and neuroprotective activity.
- Enhances serotonin modulation and neuroplasticity.
Synergy: Pairs with Kanna, Ashwagandha, and PS for multi-modal mood support.
- Lopresti AL et al. J Integr Med. 2018;16(1):59–72.
- Hausenblas HA et al. J Affect Disord. 2013;150(2):e90–e99.
- Papandreou MA et al. Psychiatry Res. 2014;215(1):97–101.
- Shafiee M et al. Hum Psychopharmacol. 2018;33(6):e2673.
Synergy Overview
This formula was strategically designed to address stress resilience, cognitive performance, mood stability, energy production, and immune modulation through tightly coordinated ingredient interactions.
Stress and HPA Regulation: Adaptogens such as Rhodiola, Ashwagandha, Reishi, Schisandra, and Magnolia work synergistically to reduce cortisol, enhance resilience, and balance the hypothalamic-pituitary-adrenal axis.
Mood and Emotional Tone: Ingredients including Phosphatidylserine, Saffron, Kanna, Theanine, and B-complex vitamins modulate neurotransmitters and promote emotional stability and calm focus.
Cognitive Clarity and Performance: Phosphatidylserine, Ginseng, Rhodiola, Theanine, and B12 work together to enhance memory, attention, and mental stamina.
Energy and Mitochondrial Support: Magnesium, B-complex, Ginseng, and Rhodiola support cellular energy generation through improved ATP synthesis and oxygen efficiency.
Immune and Inflammatory Modulation: Reishi, Schisandra, and Ashwagandha enhance immune surveillance and deliver antioxidant and anti-inflammatory activity to maintain systemic balance.
FAQ
Q: What are the biggest difference in the new version?
A: The new CALM formula takes a major leap forward, evolving from primarily cortisol and relaxation product into a multi-pathway mood, cognition, and stress resilience blend. It includes targeted nootropics, clinical mineral support, and broader adaptogen diversity while keeping the core tranquil botanicals intact.
Q: What new ingredients were added?
A: The new version introduces 7 new or upgraded ingredients for next-level mood and calm support:
- Aquamin® Magnesium (40 mg) – supports GABA activity, stress buffering
- B-Vitamin Complex (B3, B6, B12, Folate, Pantothenic Acid) – neurotransmitter cofactor support
- Phosphatidylserine (now 600 mg vs. 200 mg) – cognition + cortisol modulation
- Rhodiola (6% salidrosides, 300 mg) – energizing stress adaptogen
- Reishi (250 mg, 4:1) – emotional and immune balance
- Schisandra (250 mg) – mood, liver, and energy synergy
- Saffron (30 mg, 0.3% Safranal) – mood elevation and serotonin modulation
Q: What stayed the same?
A: Several key actives from the original formula remain:
- L-Theanine (300 mg) – calm, focused relaxation
- Magnolia Bark (300 mg) – stress and sleep support
- Ginseng (now listed with Ginsenosides) – energy/adaptogen (300 → 200 mg)
- Shoden® Ashwagandha (120 mg) – high-potency adaptogen
- Kanna (Sceletium tortuosum, 50 mg) – mood and emotional resilience
- Phosphatidylserine – increased from 200 mg to 600 mg
Q: What was removed?
A: Only Lemon Balm (300 mg) and Lithium Orotate (5 mg) were removed.
These were replaced with more synergistic mood and mitochondrial regulators like B vitamins, Rhodiola, Reishi, and Saffron, which offer broader coverage and stronger efficacy in daily mood and emotional balance.
Q: Is the new version more effective?
A: Yes, the formula has been updated to be our most advanced yet:
- Combines stress resilience + focus + emotional mood support
- Adds neurotransmitter cofactor vitamins (B6, B12, Folate)
- Features mitochondrial adaptogens (Rhodiola, Schisandra) and recovery agents (Reishi, Saffron)
- Boosts Phosphatidylserine to 600 mg — major cortisol and cognition upgrade
- Includes Aquamin® magnesium for nerve and GABA support
Q: How should I take it?
A:
- Consume four (4) capsules daily
- Best Timing: Morning for stress balance and mood uplift; or split AM/PM
- With Food: Yes, preferably with food for vitamin, mineral, and herbal absorption
- Stacks With: ADAPTOGEN, BRAIN, or stimulant-based nootropics or pre-workouts
- Cycle: No cycling needed, designed for safe daily use
Q: Who is this best for?
A:
- Anyone managing daily stress, irritability, or mood swings
- Professionals or parents who want calm focus without sedation
- People prone to overstimulation, anxiety, or burnout
- Users who want a non-habit-forming, complete stress formula



