BIOME: GUT + DIGESTION SUPPORT

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BIOME: GUT + DIGESTION SUPPORT

Nutrient Uptake • Microbiome Balance • GI Support

BIOME is an all-in-one gut health formula combining probiotics, prebiotics, enzymes, and gut-repair nutrients to restore digestive balance, enhance immunity, and support a healthy microbiome. 

Key Benefits:

• Supports digestion and nutrient absorption
  

• Promotes a healthy microbiome and immune function
  

• Helps reduce bloating, gas, and GI inflammation
  

• Combines CoreBiome®, probiotics, enzymes, and mucosal support
  
  

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Zinc (from PepZinGI™ Zinc-L-Carnosine Complex) – 16 mg (150%)

A complex of elemental zinc bound to L-carnosine, designed to support gastrointestinal lining and zinc bioavailability.

• Supports stomach lining integrity and promotes gut healing.
• Enhances immune defense by regulating T-cell function.
• Aids in enzyme activity essential for digestion and DNA repair.
• Promotes intestinal mucosal repair and resistance to inflammation.

Synergy: Works with gut-support agents (like licorice and CoreBiome) to fortify gut wall integrity.

• Matsukura N, Tanaka N. Aliment Pharmacol Ther. 2000;14 Suppl 1:8–13.
• Prasad AS. Curr Opin Clin Nutr Metab Care. 2009;12(6):646–652.
• Wada T et al. J Pharmacol Sci. 2007;104(1):27–35.

 

Guar Gum Fiber Powder – 1,000 mg

A water-soluble dietary fiber derived from the guar bean (Cyamopsis tetragonolobus).

• Promotes bowel regularity and stool normalization.
• Serves as a prebiotic, supporting healthy gut flora.
• Slows gastric emptying to enhance nutrient absorption.
• May aid in regulating blood glucose levels post-meal.

Synergy: Enhances probiotic colonization by supplying fermentable substrate.

• Slavin JL. Adv Nutr. 2013;4(2):141–150.
• Jovanovski E et al. Am J Clin Nutr. 2019;109(2):471–487.

 

CoreBiome® Tributyrin – 545 mg

A patented short-chain fatty acid (SCFA) source delivering butyrate, crucial for gut lining integrity and microbiome health.

• Fuels colonocytes and strengthens gut epithelial barrier.
• Modulates inflammation via histone deacetylase inhibition.
• Enhances gut motility and tight junction function.
• Supports microbial diversity and immune modulation.

 

Synergy: Butyrate’s benefits are enhanced by probiotics and prebiotics (e.g., guar gum and fiber blends).

• Canani RB et al. World J Gastroenterol. 2011;17(12):1519–1528.
• van der Beek CM et al. J Nutr Biochem. 2017;42:1–11.

 

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Digexin™ (Ashwagandha Root & Okra Fruit Extracts) – 300 mg

A blend of adaptogenic Ashwagandha and antioxidant-rich okra, targeting stress and gut health.

• Reduces cortisol and enhances resilience to digestive stress.
• Ashwagandha supports GI barrier integrity and HPA axis balance.
• Okra provides mucilage and antioxidants that soothe mucosal irritation.
• Together, they support microbiome balance under stress.

Synergy: Complements zinc and butyrate for stress-induced gut disruption.

• Chandrasekhar K et al. Indian J Psychol Med. 2012;34(3):255–262.
• Lengsfeld C et al. Planta Med. 2004;70(1):62–67.

 

GutGard® DGL Licorice Extract – 155 mg

A flavonoid-rich, deglycyrrhizinated form of licorice standardized to support digestive function without raising blood pressure.

• Soothes the gastrointestinal lining and promotes mucosal defense.
• Inhibits H. pylori and supports microbiome homeostasis.
• Reduces intestinal inflammation and acid-induced damage.
• Supports upper GI comfort and ulcer resistance.

Synergy: Works with zinc-carnosine and butyrate to protect gastric epithelium.

• van Marle J et al. J Ethnopharmacol. 2006;107(2):219–224.
• Mowrey DB. Lancet. 1986;328(8505):817–818.

 

DigeZyme® Multi Enzyme Complex – 150 mg

A blend of digestive enzymes including amylase, protease, lipase, cellulase, and lactase.

• Enhances macronutrient breakdown and absorption.
• Reduces digestive discomfort and postprandial bloating.
• Supports nutrient assimilation in enzyme-deficient individuals.
• Promotes gut efficiency under high-stress, high-protein diets.

Synergy: Complements probiotics and fiber for overall digestive capacity.

• Martinsen TC et al. World J Gastroenterol. 2005;11(18):2832–2838.
• Borrelli F et al. Neurogastroenterol Motil. 2009;21(8):823–832.

 

Quadruple-Coated Probiotic Blend – 1 Billion CFU (Total)

A blend of 5 probiotic strains designed for enhanced survivability through the digestive tract.

• Supports gut microbiome diversity and colon health.
• Reinforces intestinal barrier and mucosal immunity.
• Helps manage GI upset, irregularity, and bloating.
• May improve nutrient absorption and vitamin synthesis.

Strain breakdown:

• L. rhamnosus GG (400M) – Supports immune regulation.
• L. plantarum 299v (200M) – Aids IBS symptom reduction.
• B. longum (150M) – Balances mood-gut axis and digestion.
• L. salivarius (150M) – Oral-gut crossover immunity.
• B. coagulans (100M) – Spore-forming resilience for survivability.

Synergy: Enhanced by prebiotic fiber and SCFA producers like CoreBiome.

• Ouwehand AC et al. Br J Nutr. 2002;87(S2):S153–S157.
• Marteau P et al. Gut. 2001;48(3):343–347.

 

AstraGin® (Panax notoginseng + Astragalus membranaceus) – 50 mg

• What it is: A patented adaptogenic compound shown to enhance nutrient absorption and gut integrity.
• Boosts absorption of amino acids, vitamins, and fatty acids.
• Promotes gut lining regeneration and tight junction restoration.
• Modulates gut inflammation and supports microbiome balance.
• Increases bioavailability of co-formulated ingredients.

Synergy: Amplifies uptake of zinc, butyrate, fiber, and enzymes.

• Yang H et al. J Agric Food Chem. 2014;62(30):7082–7089.
• Hu Z et al. Phytother Res. 2014;28(2):187–194.

 

Synergy Overview

Barrier Defense: Zinc carnosine, licorice, butyrate, and ashwagandha strengthen epithelial walls.

Digestive Efficiency: DigeZyme enzymes and probiotics improve nutrient breakdown and utilization.

Microbiome Balance: Prebiotic fiber, CoreBiome butyrate, and probiotics shape beneficial gut flora.

Absorption Optimization: AstraGin boosts bioavailability and nutrient uptake across the board.

 

 

FAQ

Q: What are the major changes in the new BIOME formula?

A: The new version significantly increases the serving size from 2 to 4 capsules and introduces three new functional gut health ingredients:

• Guar Gum Fiber (1,000mg) – for prebiotic support and gut motility
• Digexin™ Ashwagandha + Okra Extract (300mg) – targeted gut-brain axis and mucosal integrity

Q: Were any ingredients removed or reduced?

A: No ingredients were removed. All previous actives remain at identical dosages, including:

• CoreBiome® Tributyrin (545mg)
• GutGard® DGL (155mg)
• DigeZyme® (150mg)
• Quad-strain probiotic blend (1 Billion CFU total)
• PepZinGI® Zinc-L-Carnosine (75mg)
• AstraGin® (50mg)

Q: Why were these new ingredients added?

A: The additions improve total gut support by addressing:

• Prebiotic fiber (Guar Gum) to feed beneficial bacteria
• Anti-inflammatory + mucosal repair synergy (Ashwagandha + Okra)
• A more complete strain diversity for probiotic coverage

Q: How should I use the new version?

A: The new serving is 4 vegetable capsules daily, compared to 2 previously. It can be taken all at once or split across the day (e.g., 2 with breakfast, 2 with dinner). No refrigeration needed.

Q: What’s the benefit of the upgrade?

A: The new BIOME formula evolves from a foundational gut health product into a multidimensional microbiome optimizer, covering probiotics, prebiotics, digestive enzymes, mucosal repair, and gut-brain axis signaling in one formula.