Chinese Skullcap (Scutellaria baicalensis) – 1,000 mg
A flavonoid-rich botanical containing baicalin and baicalein with strong GABAergic and anxiolytic properties.
- Promotes calmness through GABA receptor modulation
- Reduces anxiety and nervous system overactivity
- Supports neuroprotection and anti-inflammatory signaling
- Enhances sleep quality and relaxation depth
- May reduce cortisol and stress-related excitability
Synergy: Works with valerian, theanine, and apigenin to amplify GABAergic tone and reduce sleep latency.
- Awad R et al. Phytother Res. 2003;17(1):1–8.
- Zhang DY et al. J Ethnopharmacol. 2013;150(2):593–599.
- Hui KM et al. J Ethnopharmacol. 2000;72(3):483–487.
Valerian (Valeriana officialis) Extract – 1,000 mg
A well-established sleep botanical standardized for valerenic acids that influence GABA signaling.
- Improves sleep onset and reduces time to fall asleep
- Enhances deep sleep quality
- Reduces nighttime awakenings
- Supports nervous system relaxation
- May reduce mild anxiety and restlessness
Synergy: Combines with skullcap, theanine, and magnolia to produce multi-pathway GABAergic sedation without heavy next-day grogginess.
- Bent S et al. Am J Med. 2006;119(12):1005–1012.
- Fernández-San-Martín MI et al. Sleep Med. 2010;11(6):505–511.
- Hattesohl M et al. Phytomedicine. 2008;15(1–2):2–15.
L-Theanine – 500 mg
A calming amino acid that promotes relaxation without sedation via alpha-wave brain activity.
- Increases alpha brain waves (relaxed alertness)
- Reduces stress and sympathetic activation
- Improves sleep quality and calmness
- Supports focus without overstimulation
- Helps blunt cortisol and excitatory signaling
Synergy: Works with GABAergic herbs (valerian, skullcap) and serotonin precursors (5-HTP) to balance relaxation and sleep depth.
- Nobre AC et al. Brain Topogr. 2008;22(2):41–48.
- Kimura K et al. Biol Psychol. 2007;74(1):39–45.
- Unno K et al. J Funct Foods. 2013;5(4):1238–1244.
5-HTP (Griffonia simplicifolia) – 300 mg
A direct precursor to serotonin, which is further converted into melatonin.
- Increases serotonin levels
- Supports melatonin production
- Improves sleep onset and mood
- Reduces nighttime wakefulness
- Supports emotional calmness
Synergy: Works upstream of melatonin while pairing with theanine and magnolia to improve both mood and sleep architecture.
- Birdsall TC. Altern Med Rev. 1998;3(4):271–280.
- Turner EH et al. J Clin Psychopharmacol. 2006;26(4):379–381.
- Shaw K et al. Cochrane Database Syst Rev. 2002;(1):CD003198.
Magnolia Bark (Magnolia officinalis) – 300 mg
A calming botanical rich in honokiol and magnolol with anxiolytic and sleep-enhancing effects.
- Reduces anxiety and stress signaling
- Improves sleep onset latency
- Enhances GABA receptor activity
- Provides antioxidant neuroprotection
- Supports cortisol regulation
Synergy: Works with theanine, valerian, and skullcap to deepen relaxation while complementing melatonin signaling.
- Kuribara H et al. J Ethnopharmacol. 1999;65(2):157–162.
- Chioca LR et al. Evid Based Complement Alternat Med. 2009;6(3):273–281.
- Kang SS et al. Int J Mol Sci. 2017;18(6):1298.
PeptiSleep™ (Rice Protein Hydrolysate) – 250 mg
A bioactive peptide complex designed to promote relaxation and improve sleep quality.
- Enhances parasympathetic nervous system activity
- Improves sleep depth and continuity
- Reduces sleep fragmentation
- Supports recovery and nighttime relaxation
- May improve next-day alertness
Synergy: Works with melatonin and GABAergic compounds to enhance full sleep-cycle regulation and recovery.
- Uchida S et al. J Nutr Sci Vitaminol. 2010;56(1):36–42.
- Yamadera W et al. Sleep Biol Rhythms. 2007;5(4):247–252.
Mucuna pruriens (98% L-DOPA) – 150 mg
A natural source of L-DOPA that supports dopamine production and neurological balance.
- Supports dopamine synthesis
- Enhances mood and mental relaxation
- May reduce stress-induced fatigue
- Supports motivation and emotional stability
- Balances neurotransmitter tone
Synergy: Works with 5-HTP to balance serotonin and dopamine, while calming agents prevent overstimulation.
- Manyam BV. J Altern Complement Med. 1995;1(3):249–255.
- Katzenschlager R et al. J Neurol Neurosurg Psychiatry. 2004;75(12):1672–1677.
- Nagashayana N et al. Phytother Res. 2000;14(6):459–463.
Apigenin – 100 mg
A flavonoid found in chamomile with strong anxiolytic and GABA-modulating properties.
- Promotes relaxation and sleep onset
- Enhances GABA receptor binding
- Reduces anxiety and stress
- Supports antioxidant brain protection
- Improves sleep quality
Synergy: Amplifies effects of valerian, skullcap, and magnolia through shared GABAergic pathways.
- Viola H et al. Planta Med. 1995;61(3):213–216.
- Zanoli P et al. Fitoterapia. 2000;71 Suppl 1:S117–S123.
- Shinomiya K et al. Eur J Pharmacol. 2005;521(1–3):87–91.
Quercetin – 100 mg
A flavonoid antioxidant that supports inflammation control and sleep-related recovery pathways.
- Reduces oxidative stress
- Supports immune balance
- May improve sleep quality via inflammation reduction
- Enhances cellular recovery
- Supports cardiovascular health
Synergy: Works with apigenin and magnolia to reduce neuroinflammation and improve overall sleep environment.
- Li Y et al. Nutrients. 2016;8(3):167.
- Boots AW et al. Eur J Pharmacol. 2008;585(2–3):325–337.
- Bischoff SC. Nutrients. 2008;138(2):256–262.
Rutaecarpine – 100 mg
A bioactive alkaloid known for thermogenic and circulatory modulation, often used to support stimulant clearance.
- Supports vasodilation and circulation
- Enhances metabolic clearance pathways
- May help reduce stimulant half-life effects
- Supports cardiovascular function
- Promotes nighttime relaxation indirectly
Synergy: Complements melatonin and calming compounds by helping reduce lingering stimulant effects.
- Morinaga H et al. Hypertension. 2001;37(2):585–590.
- Wang GJ et al. J Cardiovasc Pharmacol. 1997;30(5):647–652.
Melatonin (MicroActive® + Standard) – 5 mg total
A dual-phase delivery system combining immediate and sustained-release melatonin.
- Regulates circadian rhythm
- Speeds sleep onset
- Maintains sleep throughout the night
- Improves sleep quality and duration
- Supports recovery and hormonal balance
Synergy: Works downstream of 5-HTP while being supported by GABAergic and adaptogenic compounds for full-spectrum sleep optimization.
- Brzezinski A. N Engl J Med. 1997;336(3):186–195.
- Zhdanova IV et al. Sleep. 2001;24(2):225–230.
- Ferracioli-Oda E et al. PLoS One. 2013;8(5):e63773.
Synergy Overview
This formula is engineered specifically for complete sleep architecture optimization, targeting onset, depth, and recovery—not just sedation.
Sleep Onset Acceleration: 5-HTP, melatonin, theanine, apigenin, and magnolia work together to rapidly transition the brain into a sleep-ready state by increasing serotonin → melatonin conversion and enhancing GABA signaling.
Deep Sleep + Maintenance: Valerian, skullcap, PeptiSleep™, and sustained-release melatonin ensure prolonged sleep duration and reduced nighttime awakenings through multi-pathway CNS calming.
Neurotransmitter Balance: Mucuna (dopamine) and 5-HTP (serotonin) create balanced mood and relaxation signaling, preventing the “wired but tired” state common in poor sleep.
Stress + Cortisol Reduction: Magnolia, theanine, and skullcap reduce sympathetic nervous system activity and cortisol, allowing the body to fully shift into parasympathetic recovery mode.
Recovery + Anti-Inflammation: Quercetin and apigenin reduce oxidative stress and inflammation, improving sleep quality and next-day recovery.
Stimulant Offset + Night Optimization: Rutaecarpine enhances clearance of stimulants, making this formula highly effective even for users who consume caffeine later in the day.
FAQ
Q: What are the biggest differences in the new DEEP SLEEP formula?
A: This formula moves beyond basic sleep aids and becomes a multi-phase sleep system:
- Dual-phase melatonin (immediate + sustained)
- Full neurotransmitter support (serotonin + dopamine + GABA)
- Clinically dosed calming botanicals
- Added recovery and anti-inflammatory compounds
- Built-in stimulant clearance support (rutaecarpine)
Q: What was improved vs the old formula?
A:
- More comprehensive GABAergic stack (skullcap + valerian + apigenin + magnolia)
- Higher-end sleep peptide (PeptiSleep™)
- Dual-delivery melatonin system
- Added neurotransmitter balancing (Mucuna + 5-HTP combo)
- Inclusion of rutaecarpine for real-world use (caffeine users)
Q: Is this stronger than typical sleep formulas?
A: Yes, but more importantly, it’s smarter:
- Doesn’t rely on just sedation
- Targets multiple pathways simultaneously
- Supports both falling asleep AND staying asleep
- Improves next-day recovery instead of grogginess
Q: How should I take it?
A:
- Take up to 6 capsules 15–30 minutes before bed
- Can adjust dose based on tolerance (flexible dosing)
- Best taken without food for faster onset
- Ideal for nightly use or as needed
- Can be stacked with NIGHTCAP, CALM, and CORTISOL CONTROL to further augment sleep and stress management
Q: Who is this best for?
- People who struggle to fall asleep
- People who wake up during the night
- High-stress individuals with overactive minds
- Caffeine/stimulant users needing better nighttime shutdown
- Anyone wanting deep, restorative sleep without next-day fog